Background: The human head louse, Pediculus humanus capitis, is a cosmopolitan blood-sucking ectoparasite affecting mostly schoolchildren in both developed and developing countries. In Honduras, chemical pediculicides are the first line of treatment, with permethrin as their main active ingredient. Despite the extended use of these products, there is currently no research investigating insecticide resistance in Honduran head lice. In head lice, the most common mechanism is knockdown resistance (kdr), which is the result of two point mutations and the associated amino acid substitutions, T917I and L920F, within the voltage-sensitive sodium channel (VSSC)…
…To our knowledge, this is the first study showing the presence of the C/T mutation responsible of the T917I kdr allele associated with pyrethroid resistance in P. h. capitis from Honduras. The PCR-restriction fragment length polymorphism (RFLP) employed here has demonstrated to be a reliable, economic, and reproducible assay that can be used to accurately genotype individual head lice for the mutation encoding the resistance-conferring T917I amino acid substitution. This highlights the necessity of proactive resistance management programmes designed to detect pyrethroid mutations before they become established within populations of head lice.
Parasit Vectors. 2020 Jun 16;13(1):312. doi: 10.1186/s13071-020-04183-2.
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National Pediculosis Association,® Inc.
National Pediculosis Association Mission Statement
The NPA is a 501(c)(3) non-profit organization dedicated since 1983 to protecting children, their families and their environment from the misuse and abuse of prescription and over-the-counter pesticide treatments for lice and scabies.Pediculosis (the medical term for an infestation of lice) provides a public health opportunity to teach important lessons about communicable disease preparedness, responsible personal behaviors, environmental health, and the importance of learning about pharmaceutical remedies before using them on our children and ourselves.
NPA is committed to setting the highest possible public health standards for children as they relate to the communicability and treatment of head lice. NPA has been the leader in raising pediculosis as a public health priority and a pioneer in public health education and research on pediculosis.
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The NPA developed the LiceMeister® comb in 1997 to accomplish its mission by providing a higher standard for lice combing tools and a safe, cost-effective treatment alternative to pesticides. All proceeds from sales of the LiceMeister comb allow the NPA to be self-sustaining and independent from product manufacturers while accomplishing its mission of protecting children from the misuse and abuse of pesticide treatments for lice.
Since 1997, the LiceMeister comb has been the preferred choice of many health professionals and the gold standard in combing tools for lice and nits (lice eggs). It is an FDA cleared medical device (510K) for the purposes of routine screening, early detection and removal of lice and nits, and it is the only comb to carry the name of the National Pediculosis Association.
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Since 1997, the LiceMeister comb has been the preferred choice of many health professionals and the gold standard in combing tools for lice and nits (lice eggs). It is an FDA cleared medical device (510K) for the purposes of routine screening, early detection and removal of lice and nits, and it is the only comb to carry the name of the National Pediculosis Association.
Please see our Privacy Policy, our Terms of Use and Disclaimer.
Visit the Lindane Education and Research Network | Lindane.org and malathion.org.