{"id":2720,"date":"2020-01-21T06:51:00","date_gmt":"2020-01-21T11:51:00","guid":{"rendered":"https:\/\/www.headlice.org\/comb\/?p=2720"},"modified":"2020-04-25T06:56:57","modified_gmt":"2020-04-25T10:56:57","slug":"rickettsia-prowazekii-epidemic-typhus","status":"publish","type":"post","link":"https:\/\/www.headlice.org\/comb\/rickettsia-prowazekii-epidemic-typhus\/","title":{"rendered":"Rickettsia Prowazekii (Epidemic Typhus)"},"content":{"rendered":"\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p><em>Rickettsia prowazekii<\/em>\u00a0is an intracellular, gram-negative coccobacillus. It is an obligate parasite.\u00a0<em>R. prowazekii<\/em>\u00a0belongs to the genus Rickettsia and is the causative agent of epidemic typhus.\u00a0The genus Rickettsia is composed of gram-negative bacteria. Rickettsiae are the closest known relatives of mitochondria in eukaryotic cells.<\/p><p>The vector for epidemic typhus is the human body louse.\u00a0<em>R. prowazekii<\/em>\u00a0multiplies in the gut epithelium of the body louse and explodes into the gastrointestinal (GI) tract, eventually killing the body louse in the process. In this regard,\u00a0<em>R. prowazekii<\/em>\u00a0is unique because no other known members of Rickettsia kill their vector. The\u00a0<em>R. prowazekii<\/em>\u00a0remain viable in the dead louse as well as in the louse feces.\u00a0 Viable\u00a0<em>R. prowazekii\u00a0<\/em>have been detected in dried feces of the body louse for up to several months. \u00a0It is the only member of the genus\u00a0<em>Rickettsia<\/em>\u00a0to cause a latent infection, manifesting years to decades later, known as Brill-Zinsser disease (BZD). BZD was first described in 1913 and occurs because of reactivation of\u00a0<em>R. prowazekii.<\/em><\/p><cite>Article Author: Sami Akram<br>Article Editor: Vidhya Prakash<br>PubMed Link: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/n\/statpearls\/article-599\">Rickettsia Prowazekii (Epidemic Typhus)<\/a><\/cite><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>Rickettsia prowazekii\u00a0is an intracellular, gram-negative coccobacillus. It is an obligate parasite.\u00a0R. prowazekii\u00a0belongs to the genus Rickettsia and is the causative agent of epidemic typhus.\u00a0The genus Rickettsia is composed of gram-negative bacteria. Rickettsiae are the closest known relatives of mitochondria in eukaryotic cells. The vector for epidemic typhus is the human body louse.\u00a0R. prowazekii\u00a0multiplies in the &hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[40,33],"tags":[],"class_list":{"0":"post-2720","1":"post","2":"type-post","3":"status-publish","4":"format-standard","6":"category-human-louse-and-disease","7":"category-news","8":"entry"},"featured_image_src":null,"featured_image_src_square":null,"author_info":{"display_name":"NPA","author_link":"https:\/\/www.headlice.org\/comb\/author\/moore\/"},"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_likes_enabled":false,"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/posts\/2720","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/comments?post=2720"}],"version-history":[{"count":1,"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/posts\/2720\/revisions"}],"predecessor-version":[{"id":2721,"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/posts\/2720\/revisions\/2721"}],"wp:attachment":[{"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/media?parent=2720"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/categories?post=2720"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/tags?post=2720"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}