{"id":2718,"date":"2010-09-25T06:45:00","date_gmt":"2010-09-25T10:45:00","guid":{"rendered":"https:\/\/www.headlice.org\/comb\/?p=2718"},"modified":"2020-04-25T06:50:45","modified_gmt":"2020-04-25T10:50:45","slug":"brill-zinsser-disease-in-a-patient-following-infection-with-sylvatic-epidemic-typhus-associated-with-flying-squirrels","status":"publish","type":"post","link":"https:\/\/www.headlice.org\/comb\/brill-zinsser-disease-in-a-patient-following-infection-with-sylvatic-epidemic-typhus-associated-with-flying-squirrels\/","title":{"rendered":"Brill-Zinsser Disease in a Patient Following Infection with Sylvatic Epidemic Typhus Associated with Flying Squirrels"},"content":{"rendered":"\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>Brill-Zinsser disease is a form of recrudescent epidemic typhus that occurs years or decades after primary typhus infection [<a>1\u20134<\/a>]. However, in the United States, improved sanitation and hygiene measures have largely eliminated the human body louse vector and epidemic typhus as public health concerns\u00a0<a>[1]<\/a>. In addition, the availability of tetracycline-class antibiotics to effectively treat rickettsial infections has reduced the severity and duration of infections [<a>1<\/a>,\u00a0<a>4<\/a>].<\/p><p>Although the classic louseborne cycle of\u00a0<em>Rickettsia prowazekii<\/em>\u00a0is not common in the United States,\u00a0<em>R. prowazekii<\/em>\u00a0infections are still sporadically reported. There have been at least 47 cases documented in humans since 1976 (Centers for Disease Control and Prevention, unpublished data) [<a>5<\/a>,\u00a0<a>6<\/a>]. Most of these cases had reported contact prior to illness onset with the southern flying squirrel,\u00a0<em>Glaucomys volans,<\/em>\u00a0which serves as a zoonotic reservoir for a sylvatic cycle of infection [<a>5<\/a>,\u00a0<a>6<\/a>]. In this report, we describe the first known reported case of Brill-Zinsser disease following a primary infection with sylvatic epidemic typhus acquired from flying squirrels.<\/p><cite><em>Clinical Infectious Diseases<\/em>, Volume 51, Issue 6, 15 September 2010, Pages 712\u2013715,\u00a0<a href=\"https:\/\/doi.org\/10.1086\/655891\">https:\/\/doi.org\/10.1086\/655891<\/a><\/cite><\/blockquote>\n\n\n\n\n","protected":false},"excerpt":{"rendered":"<p>Brill-Zinsser disease is a form of recrudescent epidemic typhus that occurs years or decades after primary typhus infection [1\u20134]. However, in the United States, improved sanitation and hygiene measures have largely eliminated the human body louse vector and epidemic typhus as public health concerns\u00a0[1]. In addition, the availability of tetracycline-class antibiotics to effectively treat rickettsial &hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[40,33],"tags":[],"class_list":{"0":"post-2718","1":"post","2":"type-post","3":"status-publish","4":"format-standard","6":"category-human-louse-and-disease","7":"category-news","8":"entry"},"featured_image_src":null,"featured_image_src_square":null,"author_info":{"display_name":"NPA","author_link":"https:\/\/www.headlice.org\/comb\/author\/moore\/"},"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_likes_enabled":false,"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/posts\/2718","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/comments?post=2718"}],"version-history":[{"count":1,"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/posts\/2718\/revisions"}],"predecessor-version":[{"id":2719,"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/posts\/2718\/revisions\/2719"}],"wp:attachment":[{"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/media?parent=2718"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/categories?post=2718"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.headlice.org\/comb\/wp-json\/wp\/v2\/tags?post=2718"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}