Reversible neurotoxicity
after an overdose of topical lindane in an
infant.
Bhalla M, Thami GP.
Department
of Dermatology and Venereology, Government Medical College Hospital,
Chandigarh, India.
Lindane (gamma benzene hexachloride) is a
widely prescribed topical scabicide because of its efficacy and
cost-effectiveness. Although toxicity from a single proper application
of lindane is generally not observed, the hazards of repeated
applications, industrial exposure, and accidental ingestion have been
well documented. We herein describe an infant with reversible
neurotoxicity following repeated applications of 1% lindane for the
treatment of scabies. The role of factors predisposing to increased
absorption and the recommendations to minimize potential neurotoxicity
are emphasized.
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