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(1α,2α,3β,4α,5α,β)-1,2,3,4,5,6-hexachlorocyclohexane
1α,2α,3β,4α,5α,6β-hexachlorocyclohexane

gamma-Hexachlorocyclohexane

58-89-9

γ-HCH

Chime image

Known to bind to GABAA receptor.

• GABA is the major inhibitory neurotransmitter.
• Inhibiting GABAA receptor can explain many of the effects of lindane, such as anorexia, hypothermia, and persistent seizures.

We believe that lindane may also bind to the PBR.

• Lindane is known to bind in brain and steroidogenic tissues, where the PBR is located.

 www.mcnair.ucdavis.edu/presentations/1998/

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MeSH Heading

• Lindane

Mixture Name

• Kwell

Name of Substance

• Lindane
• Lindane [USAN:BAN:INN]

Superlist Name

• Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3beta,
  4alpha,5alpha,6beta)-
• HCH, technical grade [Hexachlorocyclohexanes]
• Hexachlorocyclohexane, gamma isomer
• Hexachlorocyclohexane, gamma-
• Lindane
• Lindane (all isomers)
• Lindane [Hexachlorocyclohexanes]
• RCRA waste no. U129
• gamma-BHC
• gamma-HCH [Hexachlorocyclohexanes]
• gamma-Hexachlorocyclohexane
  [Lindane and other hexachlorocyclohexane isomers]

Systematic Name

• Cyclohexane, 1,2,3,4,5,6-hexachloro-, (1alpha,2alpha,3beta,
  4alpha,5alpha,6beta)-
• Cyclohexane,1,2,3,4,5,6-hexachloro-, gamma-isomer
• gamma-HCH or gamma-BHC
• gamma-Hexachlorocyclohexane
  

Classification Code

• Agricultural Chemical
• Carcinogens
• Drug / Therapeutic Agent
• Fungicide, bactericide, wood preservative
• Human Data
• Insecticide
• Insecticides, organochlorine
• Mutation data
• Pediculicide
• Reproductive Effect
• Scabicide
• Tumor data

Superlist Classification Code

• ATSDR Profile Priority List, rank : 32
• Reasonably anticipated to be a carcinogen
• Reportable Quantity (RQ) = 1 lb
• TWA (0.5 ppm); skin;
• TWA 0.5 mg/m3; skin; Animal carcinogen
• Threshold Planning Quantity (TPQ)= 1000/10000 lb
  

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