| Metabolites of Lindane
Metabolites: Any substances produced by biological
processes, such as those from pesticides.
(EPA Terms of
Environment)
chlorine
phosgene 75-44-5 COCl 2
ICSC:
0007
dioxin
hexane
gamma-Hexachlorocyclohexane
degradation - Standard metabolic pathway
- 1,2,4-Trichlorobenzene
- 2,3,5-trichlorophenal
- 2,4,5-trichlorophenal
- 2,4,6-trichlorophenal
88-06-2
- 2,3,5,6-tetrachlorophenal
935-95-5 C 6H
2Cl 4O
ICSC:
0573
- dihydroxychlorobenzene
- dihydroxychlorobenzenes
95-88-5
- pentachlorophenal
C 6Cl
5OH 87-86-5 ICSC:
0069
- 3,6-hexachlorocyclohexane
- 4,5-hexachlorocyclohexane
- pentachlorocyclohexane
319-94-8
- dichlorophenals
- 2,3,4,6-tetrachlorophenal
- pentachlorobenzene
C 6HCl
5 608-93-5
ICSC: 0531
1,2,3,4,5-Pentachlorobenzene
- halogenated hydrocarbon epoxide
- 2,4-DICHLOROPHENOL
120-83-2
2,5-DICHLOROPHENOL
3,5-DICHLOROPHENOL
- 2,3,4-TRICHLOROPHENOL
2,3,5-TRICHLOROPHENOL
2,3,6-TRICHLOROPHENOL
2,4,5-TRICHLOROPHENOL
2,4,6-TRICHLOROPHENOL
Epoxide forms during metabolism of pentachlorocyclohexane.
This stable halogenated hydrocarbon epoxide may be responsible for the mutagenic
and carciogenic effects. (ATSDR, 1997)
- BENZENE HEXACHLORIDE
- gamma-BENZENE HEXACHLORIDE
- BENZENE HEXACHLORIDE-gamma isomer
- HEX
- gamma-HEXACHLOR
- HEXACHLORAN
- HEXACHLORANE
- gamma-HEXACHLORBENZENE
- HEXACHLOROBENZENE
- 1, 3-HEXACHLOROBUTADIENE
- HEXACHLOROBUTADIENE
- 1, 2, 3, 4, 5, 6-HEXACHLOROCYCLOHEXANE
- HEXACHLOROCYCLOHEXANE
- HEXANE
- n-HEXANE
- gamma-HEXANE LINDANE
In aminals gamma-(HCH) appears tranformed by heptic
enzymes to form the following metabolites.
- 2-CHLOROPHENOL
- o-CHLOROPHENOL
- CHLOROBENZENE ICSC:
0642
- CHLOROCYCLOHEXANE
- CHLOROCYCLOHEXANAL
- conjugates of mercapturic
acid, gluronide, and sulfate
(Chadwick and Freal 1972a; Chadwick et al. 1978a;
Engst et al.1979; Kujawa et al. 1977)
Safety
Card -- 1-HYDROXY-2,5-DICHLOROBENZENE 583-78-8 SK8600000
Safety Card --
1-HYDROXY-3, 5-DICHLOROBENZENE 591-35-5 SK8820000
Safety Card --
4-HYDROXYCHLOROBENZENE 106-48-9 SK2800000
Safety Card --
3-HYDROXYCHLOROBENZENE 108-43-0 SK2450000
Safety Card --
2-HYDROXYCHLOROBENZENE 95-57-8 SK2625000
Safety Card --p-NITROCHLOROBENZENE
100-00-5 CZ1050000
Safety Card -- O-NITROCHLOROBENZENE
88-73-3 CZ0875000
Safety Card --
ORTHO-DICHLOROBENZENE 95-50-1 CZ4500000
Safety Card --
PARA-DICHLOROBENZENE 106-46-7 CZ4550000
Safety Card --PENTACHLOROBENZENE
608-93-5 DA6640000
Safety Card --
1,2,3,4,5-PENTACHLOROBENZENE 608-93-5 DA6640000
Safety Card --
PERCHLOROBENZENE 118-74-1 DA2975000
Safety Card -- S-TETRACHLOROBENZENE
95-94-3 DB9450000
Safety Card -- SYM-TRICHLOROBENZENE
108-70-3 DC2100100
Safety Card
--1,2,4,5-TETRACHLOROBENZENE 95-94-3 DB9450000
Safety Card
--1,3,5-TRICHLOROBENZENE 108-70-3 DC2100100
Fisher
- Chlorobenzene, Spectrophotometric Grade 108-90-7
Fisher
- Chlorobenzene, Reagent ACS (GC) 108-90-7
Safety
Card --1,3,5-TRICHLOROBENZENE 108-70-3 DC2100100
Safety Card
--1,2,4-TRICHLOROBENZENE 120-82-1 DC2100000
Safety Card --
1,2,6-TRICHLOROBENZENE 87-61-6 DC2095000
Safety Card
--1,2,3-TRICHLOROBENZENE 87-61-6 DC2095000
Safety Card --
UNSYM-TRICHLOROBENZENE 120-82-1 DC2100000
Safety Card -- VIC-TRICHLOROBENZENE
87-61-6 DC2095000
Fisher
- Chlorobenzene 108-90-7
Fisher
- Chlorobenzene 108-90-7
Fisher
- 1,3-Dichlorobenzene 541-73-1
Fisher
- 1,4-Dichlorobenzene 106-46-7
Fisher
- o-Dichlorobenzene 95-50-1
Fisher
- p-Dichlorobenzene 106-46-7
Fisher
- 1,2-Dichlorobenzene 95-50-1
Fisher
- Hexachlorobenzene 118-74-1
Fisher
- 1,2,4-Trichlorobenzene 120-82-1
Fisher
- 1,2,4-Trichlorobenzene 120-82-1
Fisher
- 1,3,5-Trichlorobenzene 108-70-3
Fisher
- 1,2,4-Trichlorobenzene 120-82-1
Fisher
- 1,2,3-Trichlorobenzene 87-61-6
Fisher
- 2,6-Dichlorobenzenethiol 24966-39-0
Fisher
- 4-Chlorobenzenesulfonamide 98-64-6
Fisher
- 1,2,4,5-Tetrachlorobenzene 95-94-3
Fisher
- 1,2,3,4-Tetrachlorobenzene 634-66-2
ALDRICH
CHEMICAL -- 1,2,3,4-TETRACHLOROBENZENE, 98%, 13184-9
ALDRICH CHEMICAL --
1,3-DICHLOROBENZENE, 98%, 11380-8
ALDRICH CHEMICAL --
1,4-DICHLOROBENZENE, 99+%, D5682-9
ALDRICH CHEMICAL --
1-BROMO-2,6-DICHLOROBENZENE, 99%, 16065-2
ALDRICH CHEMICAL --
CHLOROBENZENE, 99+%, SPECTROPHOTOMETRIC GRA
ALDRICH CHEMICAL --
CHLOROBENZENE, 99.9+% 27064-4
ALDRICH CHEMICAL --
HEXACHLOROBENZENE, 99% 17105-0
BAXTER HEALTHCARE BURDICK
& JACKSON DIV -- 1,2,4-TRICHLOROBENZENE
BAXTER HEALTHCARE BURDICK
& JACKSON DIV -- CHLOROBENZENE
BAXTER HEALTHCARE BURDICK
& JACKSON DIV -- O-DICHLOROBENZENE
Mallinckrodt Baker --
mercapturic acid 616-91-1
Mercapturic acid
Metabolites found following immediate exposure via gavage
or diet
- DI-, TRI-, TETRA and PENTACHLOROBENZENES
- PENTACHLOROHEXANES
- PENTACHLORO-2-CYCLOHEXEN-1-OL
- DI-, TRI-, TETRA and PENTACHLOROPHENOLS
- isomers of TETRACHLORO-2-CYCLOHEXANE-1-OL
(Chadwick and Freal 1972a; Chadwick et al. 1978a;
Engst et al.1979; Kujawa et al. 1977)
In vitro studies found gamma-(HCH) converted
to
(Gopalaswamy and Aiyer 1984)
1-Chlorocyclohexene
oxide
beta-Pentachlorocyclohexene
gamma-Pentachlorocyclohexene
Octafluorodichlorocyclohexene
CHEM
SERVICE -- 0-669, CHLOROBENZENE
CHEM SERVICE -- 1,2,4,5-TETRACHLOROBENZENE, O-688
CHEM SERVICE -- 1,2,4-TRICHLOROBENZENE, O-689
CHEM SERVICE -- 1,2-DICHLOROBENZENE, O-677
CHEM SERVICE -- 1,3-DICHLOROBENZENE, O-678
CHEM SERVICE -- 1,4-DICHLOROBENZENE, O-679
CHEM SERVICE -- F25
1,2-DICHLOROBENZENE
CHEM SERVICE -- F26
1,3-DICHLOROBENZENE
CHEM SERVICE -- F27
1.4-DICHLOROBENZENE - LABORATORY STANDARD
CHEM SERVICE -- F7
CHLOROBENZENE
CHEM SERVICE -- F8
1,2,4-TRICHLOROBENZENE - LABORATORY STANDARD
SCOTT SPECIALTY GASES --
CHLOROBENZENE
Chemical listings:
chlorinated hydrocarbon epoxide
Heptachlor epoxide (BHC- hexachlorocyclohexane)
di-, tri-, and tetrachlorophenols
ICSC: 0573
Metabolization
Derivatives: crude BHC metabolizes to beta, gamma, delta
and alpha isomers; gammma BHC metabolizes to gamma-pentachlorocyclohexene
2,3,5,6-TETRACHLOROPHENOL
Phenol, 2,3,5,6-tetrachloro-
2,3,5,6-Tetrachlorohydroxybenzene
C6H2Cl4O
Molecular mass: 231.9
CAS # 935-95-5
| hexachlorobenzene |
hexachlorobenzene is a parent pesticide |
also may occur as an impurity or metabolite
of some other pesticides (e.g., chlorothalonil, DCPA, pentachlorophenol,
picloram, quintozene) or as an environmental contaminant.) |
05-17-00, http://vm.cfsan.fda.gov/~dms/pes-chem.html
|
